Have you observed asthma patients developing degenerative valvular heart disease more frequently than non-asthmatic patients?
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The ACC/ AHA in collaboration with 11 other societies have updated the recommendations for clinicians on the prevention, detection, evaluation & management of high blood pressure in adults.
GINA 2025 highlights personalized asthma care via the Assess–Adjust–Review cycle. Diagnosis is supported by clinical evaluation, spirometry/PEF, and biomarkers. ICS-formoterol is preferred for control and relief, with stepwise escalation.
Asthma may predispose individuals to degenerative valvular heart disease, reported a UK Biobank study of nearly half a million adults. Over 13.8 years of follow-up, asthma was independently associated with higher risks of aortic stenosis (HR 1.31), aortic regurgitation (AR) (HR 1.24), mitral regurgitation (HR 1.19), & pulmonary regurgitation (HR 1.34). The link with AR weakened after adjusting for asthma medications.
Dietary omega-3 polyunsaturated fatty acids (ω-3 PUFAs) may protect against myopia in children aged 6-8 years. Those with the highest ω-3 intake had shorter axial lengths (23 vs 23.29 mm) and positive spherical equivalent (SE, 0.23 vs -0.13 D) compared with lower intake. Conversely, higher saturated fatty acid intake was tied to longer axial lengths and more negative SE versus lower intake.
In a 2-yr trial, intensive periodontal treatment (IPT; scaling, root planning ± corrective surgery) in otherwise healthy people with periodontitis reduced carotid intima-media thickness (−0.023 mm) over follow-up & enhanced endothelial function (FMD) within 2 months vs. control care. Inflammatory glycoprotein acetyl levels also reduced. Findings suggest IPT may aid in CV risk prevention by improving vascular health.
Findings from the PGDRD project in rural Dehradun showed that maternal overweight/obesity before conception and low physical activity during pregnancy were the most frequent modifiable risks for hyperglycemia in pregnancy (HIP), a known precursor of early-onset T2DM. Multiparity, recurrent vaginal infections, & polyhydramnios emerged as strong independent predictors, while prior hyperglycemia further amplified risk.
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